Pipeline and Upcoming Milestones
ALX1
Water soluble, small molecule prodrug (<500 Da) that releases the pharmacologically active metabolite, Nitric Oxide (NO) with sustained release duration of up to 8 hours. This candidate is formulated as an isotonic, buffered aqueous solution for oral inhalation via a customized PARI eFlow® nebulizer.
ALX2
Water soluble, small molecule prodrug (<500 Da) that releases the pharmacologically active metabolite, Nitric Oxide (NO) with accelerated release and durations up to 4 hours. This candidate is formulated as a pH controlled aqueous solution for oral inhalation to maximize lung deposition to alveolar macrophages.
Learn more about Nitric Oxide Prodrugs.